abstract：:In addition to juxtaarticular osteoporosis, which appears to reflect predominantly local disease mechanisms, more generalized bone loss can occur in rheumatoid arthritis (RA). The aim of this study was to compare bone mineral density (BMD) of the lumbar spine and proximal femur in RA patients versus controls and evalu...

journal_title：Clinical rheumatology

authors： Celiker R,Gökçe-Kutsal Y,Cindas A,Ariyürek M,Renda N,Koray Z,Basgöze O

更新日期：1995-07-01 00:00:00

abstract：:The coexistence of polymyositis (PM) and primary biliary cirrhosis (PBC) is rare; only nine cases have been described in English literature. We report a case of a 46-year-old woman presenting with these two autoimmune diseases. The diagnosis of PM was based on the symmetrical, proximal limb muscle weakness, elevated m...

journal_title：Clinical rheumatology

authors： Boki KA,Dourakis SP

更新日期：1995-05-01 00:00:00

abstract：:In juvenile chronic arthritis (JCA) the indices of disease activity, such as joint swelling, pain, tenderness, and limitation of motion, may poorly correlate with the degree of functional impairment. Since the improvement of functional capacity is one of the main objectives of treatment, we evaluated the effect of met...

journal_title：Clinical rheumatology

authors： Ravelli A,Viola S,Ramenghi B,Di Fuccia G,Ruperto N,Zonta L,Martini A

更新日期：1995-05-01 00:00:00

abstract：:Dual-energy X-ray absorptiometry (DXA) is actually considered as one of the most appropriate techniques for measuring bone mineral content (BMC) and bone mineral density (BMD). An anthropomorphic phantom and a 25-year-old girl were repeatedly measured, 160 times and 50 times respectively, over an 18-month period to in...

journal_title：Clinical rheumatology

authors： Reginster JY,Deroisy R,Zegels B,Jupsin I,Albert A,Franchimont P

更新日期：1995-03-01 00:00:00

abstract：:Bone mass was measured in 230 subjects with ages ranging from 15 to 54 years (110 males and 120 females), using the radiogrammetric method on the second metacarpal bone. Results of the study show that bone mass increases with age up to 34 years and then decreases, both in males and females, although males have signifi...

journal_title：Clinical rheumatology

authors： Kabeya JM,Mbuyi Muamba JM,Tozin R,Dequeker J

更新日期：1995-01-01 00:00:00

abstract：:Fourteen patients with ankylosing spondylitis (AS) were treated in a pilot study for two weeks at a Tiberias spa with a combination of hot mineral water baths and mud packs. A significant improvement was noticed in morning stiffness, finger to floor distance and the overall well-being assessment both by the patient an...

journal_title：Clinical rheumatology

authors： Tishler M,Brostovski Y,Yaron M

更新日期：1995-01-01 00:00:00

abstract：:We describe two patients with the primary antiphospholipid syndrome who presented with severe hypertension. Renal biopsy specimen provided histologic evidence of intra-renal vascular disease with intravascular microthrombosis and nephrosclerosis, without feature of proliferative glomerulopathy. Accelerated hypertensio...

journal_title：Clinical rheumatology

authors： Durand JM,Lefevre P,Kaplanski G,Casanova P,Soubeyrand J

更新日期：1994-12-01 00:00:00

abstract：:Microwave thermography is the technique of measuring natural thermal radiation from body tissues of clinical interest. It is safe, requires no control of environmental conditions and exposes the patient to no ionising radiation. In this study, we found that microwave thermography of the knee joints showed weak correla...

journal_title：Clinical rheumatology

authors： MacDonald AG,Land DV,Sturrock RD

更新日期：1994-12-01 00:00:00

abstract：:The relations between parameters obtained by clinical absorptiometric techniques, such as SPA, DPA, DXA and QCT, and geometrical and material parameters of bone structures are investigated. Two types of bone are considered: the diaphysis of a long bone, modelled as a hollow cylindrical structure consisting of compact ...

journal_title：Clinical rheumatology

authors： Van der Perre G,Lowet G

更新日期：1994-12-01 00:00:00

abstract：:Sternoclavicular septic arthritis is a rare complication of subclavian venous catheterization. We estimate that septic involvement of this joint may be as common as one in 500 catheterizations. We report two patients with insidious onset of shoulder pain, chest discomfort, low-grade fever and slight but painful swelli...

journal_title：Clinical rheumatology

authors： Aglas F,Gretler J,Rainer F,Krejs GJ

更新日期：1994-09-01 00:00:00

abstract：:The authors studied the incidence of atlanto-axial joint involvement by conventional radiography and CT in 183 patients with classical or definite rheumatoid arthritis (RA). In determining lesions the significance of factors such as age, sex, duration and severity of the disease was evaluated. Atlanto-axial subluxatio...

journal_title：Clinical rheumatology

authors： Montemerani M,Venturi C,Bracco S,Coviello G,Minari C,Fioravanti A,Marcolongo R

更新日期：1994-09-01 00:00:00

abstract：:A pair of identical twins suffering from ankylosing spondylitis is reported. One brother developed an earlier-onset disease and showed ossification of the posterior longitudinal ligament and the flavum ligament in his cervical spine. ...

journal_title：Clinical rheumatology

authors： Olivieri I,Pappone N,Padula A,Rengo C,Ruju GP,Pucino A,Trippi D,Ferri S,Pasero G

更新日期：1994-06-01 00:00:00

abstract：:Antibodies to 65Kd heat-shock protein (hsp) of mycobacterium leprae were measured by enzyme-linked immunosorbent assay (ELISA) in the three immunoglobulin classes in paired sera and synovial fluids of patients with rheumatoid arthritis (RA). Titers of anti-hsp antibody were expressed by optical density (OD) values for...

journal_title：Clinical rheumatology

authors： Oda A,Miyata M,Kodama E,Satoh H,Sato Y,Nishimaki T,Nomaguchi H,Kasukawa R

更新日期：1994-06-01 00:00:00

abstract：:The presence of nail changes was investigated in 102 patients with nodal osteoarthritis of the hand. Nail lesions were seen in 14/102 patients (13.7%), a prevalence higher than that observed in 96 controls (4/96, 4.2%; chi square 4.37, p = 0.036). An increased risk of nail changes was associated with osteoarthritis of...

journal_title：Clinical rheumatology

authors： Cimmino MA,Seriolo B,Accardo S

更新日期：1994-06-01 00:00:00

abstract：:Systemic Sclerosis (SSc; scleroderma) is associated with several immunological abnormalities, including altered proportion between lymphocyte subsets. Peripheral blood lymphocyte subsets from 25 patients with SSc were studied by two-colour flow cytometry using monoclonal antibodies against CD45RA and CD29 markers, whi...

journal_title：Clinical rheumatology

authors： Gorla R,Airò P,Malagoli A,Carella G,Prati E,Brugnoni D,Franceschini F,Cattaneo R

更新日期：1994-03-01 00:00:00

abstract：:In a great majority of patients with systemic lupus erythematosus (SLE) lymphocytotoxic antibodies (LCA) are detected. The reported prevalence depends on the methods of detection and definition of test-positivity. The pathogenetic role of LCA remains unclear. Different reports show that LCA can have an influence on mo...

journal_title：Clinical rheumatology

authors： Osman C,Swaak AJ

更新日期：1994-03-01 00:00:00

abstract：:In a patient suffering from rheumatoid arthritis, we report the first simultaneous occurrence of two side effects of low-dose methotrexate: an acute megaloblastic anaemia and a pneumonitis. A combination of methotrexate suspension, folinic acid and corticosteroids led to recovery. The correlation between the haematolo...

journal_title：Clinical rheumatology

authors： Bolla G,Disdier P,Harle JR,Verrot D,Weiller PJ

更新日期：1993-12-01 00:00:00

abstract：:Total body bone mineral content (TBBMC), total body bone mineral density (TBBMD), and regional bone mineral content (BMC) were determined with dual energy X-ray absorptiometry and correlated with different anthropometric variables in 324 normal male subjects aged 15 to 85 years, in order to obtain further knowledge of...

journal_title：Clinical rheumatology

authors： Rico H,Revilla M,Gonzalez-Riola J,Villa LF,Alvarez de Buergo M

更新日期：1993-12-01 00:00:00

abstract：:Circulating intercellular adhesion molecule-1 (ICAM-1) and 3 types of autoantibodies were measured in 30 patients with angiographical or pathological proved vasculitis. There were 18 patients with systemic vasculitis and 12 patients with cutaneous vasculitis. The measured antibodies included anti-endothelial cell anti...

journal_title：Clinical rheumatology

authors： Wang CR,Liu MF,Tsai RT,Chuang CY,Chen CY

更新日期：1993-09-01 00:00:00

abstract：:Tissue plasminogen activator (tPA), plasminogen activator inhibitor-1 (PAI-1) and von Willebrand factor (vWF), all of endothelial origin and active in the haemostasis, were analysed in 74 patients with rheumatoid arthritis. The concentrations were related to extra-articular disease and to the incidence of thromboembol...

journal_title：Clinical rheumatology

authors： Wållberg-Jonsson S,Dahlén GH,Nilsson TK,Rånby M,Rantapää-Dahlqvist S

更新日期：1993-09-01 00:00:00

abstract：:A 78-year-old Japanese woman with Sjögren's syndrome complicating immune-mediated aplastic anaemia is described. A diagnosis of aplastic anaemia was made from severe pancytopenia with hypoplastic marrow. Laboratory studies suggested an association of bone marrow suppressive T-lymphocytes with the pathogenesis of aplas...

journal_title：Clinical rheumatology

authors： Satoh M,Yamagata H,Watanabe F,Matsushita Y,Nakayama S,Murakami M,Matsuyama J,Oshima S,Akizuki M

更新日期：1993-06-01 00:00:00

abstract：:Treatment with methotrexate (MTX) is well established in rheumatoid arthritis (RA), but dosing remains arbitrary as studies on the effect of different dosing schedules are lacking. In a randomised crossover design of 20 patients with RA, the effect of low (2.5mg) oral daily doses of MTX (15 mg weekly) was compared to ...

journal_title：Clinical rheumatology

authors： Seideman P

更新日期：1993-06-01 00:00:00

abstract：:We report one case of non-Hodgkin lymphoma in a patient, with a 30-year history of rheumatoid arthritis, taking low dose methotrexate weekly over a 10-month period. The mild immunosuppression that occurs with methotrexate therapy probably places patients with rheumatoid arthritis at added risk of developing lymphoprol...

journal_title：Clinical rheumatology

authors： Taillan B,Garnier G,Castanet J,Ferrari E,Pesce A,Dujardin P

更新日期：1993-03-01 00:00:00

abstract：:Acetabular protrusion (PA) as measured by a line crossing method was studied in 73 patients with juvenile rheumatoid arthritis (JRA) and its frequency found to be 12% (9/73), presenting bilaterally in 5 cases and unilaterally in 4. All patients had some other forms of radiological damage and the presence of PA was pre...

journal_title：Clinical rheumatology

authors： Gusis SE,Maldonado Cocco JA,Rivero EM,Babini JC,Gagliardi SA

更新日期：1993-03-01 00:00:00

abstract：:Since diffuse idiopathic skeletal hyperostosis (DISH) is frequently difficult to differentiate radiologically from the axial involvement of ankylosing spondylitis and osteoarthrosis, some features of these 3 different diseases were compared. The predominantly horizontal nature of the enthesiophyte in DISH and its righ...

journal_title：Clinical rheumatology

authors： Maertens M,Mielants H,Verstraete K,Veys EM

更新日期：1992-12-01 00:00:00

abstract：:The level of the N terminal fragment of procollagen III (P3NP) levels of 100 consecutive patients affected by rheumatoid arthritis (RA) were evaluated in comparison with disease activity markers (erythrocytes sedimentation rate, C reactive protein), immunological status (rheumatoid factors, immune complexes) and joint...

journal_title：Clinical rheumatology

authors： Tebib JG,Viguier P,Noel E,Colson F,Barbier Y,Bouvier M

更新日期：1992-12-01 00:00:00

abstract：:Perforin and granzyme A co-localize in the cytotoxic granules of killer cells like cytotoxic T lymphocytes (CTL). Perforin is the cytolytic pore-forming protein, whereas the function of the homodimeric serine protease granzyme A and other members of the granzyme family is still unclear. Granzyme A-immunoreactive cells...

journal_title：Clinical rheumatology

authors： Nordström DC,Konttinen YT,Sorsa T,Nykanen P,Pettersson T,Santavirta S,Tschopp J

更新日期：1992-12-01 00:00:00

abstract：:An insufficiency fracture (IF) involving the acetabulum is presented. This fracture occurred in a 67-year-old woman who had been hysterectomized and oophorectomized 27 years earlier for a carcinoma of the uterine cervix, and who had received external pelvic irradiation. This IF location has been rarely described earli...

journal_title：Clinical rheumatology

authors： Schreiber S

更新日期：1992-09-01 00:00:00

abstract：:Four patients with rheumatoid nodulosis are here described, together with a review of cases reported to date in the literature. This particular variant of rheumatoid arthritis (RA) is characterized by the presence of subcutaneous rheumatoid nodules, scanty or absent systemic manifestations and a clinically benign cour...

journal_title：Clinical rheumatology

authors： Goñi MA,Scheines EJ,Paira SO,Barceló HA,Maldonado Cocco JA

更新日期：1992-09-01 00:00:00

abstract：:HLA B27 and other clinical findings were investigated in 18 Turkish patients with Reiter's syndrome (mean age 35.8 +/- 8.09). Male/female ratio was 2/1. All 18 patients were seronegative, 12 (66.6%) presenting with an asymmetrical oligoarticular arthritis. Radiological sacroiliitis and enthesopathy was found in 9 (50%...

journal_title：Clinical rheumatology

authors： Tuncer T,Arman MI,Akyokus A,Bütün B,Unal S

更新日期：1992-06-01 00:00:00

abstract：:This study shows that N-acetyl-galactosamine and N-acetyl-glucosamine can diminish the production of superoxide anion from cytochalasin-B treated PMNs stimulated with FMLP. Inhibition ranged from 80.9% to 1.8%. N-acetyl-galactosamine was superior to N-acetyl-glucosamine, but both showed their action in a dose-related ...

journal_title：Clinical rheumatology

authors： Kamel M,Alnahdi M

更新日期：1992-06-01 00:00:00

abstract：:Acupuncture is widely used for pain relief in many musculoskeletal disorders, and evidence suggests that modulation of the sympathetic nervous system responses which play an integral part in somatic pain, is an important mechanism of acupuncture action. This prospective study of 20 patients with neck and arm pain meas...

journal_title：Clinical rheumatology

authors： Thomas D,Collins S,Strauss S

更新日期：1992-03-01 00:00:00

abstract：:We report a case of a 53-year-old woman diagnosed of systemic sclerosis. She underwent an episode of pulmonary haemorrhage, characterized by haemoptysis, sudden anaemization, and bilateral alveolar infiltration during her hospitalization, which was resolved with steroid treatment. Subsequently, she developed a focal n...

journal_title：Clinical rheumatology

authors： Alvarez Vega JL,Salazar Vallinas JM,Ortega Alberdi R,Muñoz Sanz A,Turegano JM,Fernandez Alonso J

更新日期：1992-03-01 00:00:00

abstract：:We investigated some steps in the signal transduction pathway leading to the proliferation of synovial cells. 12-o-tetradecanoyl phorbol-13-acetate (TPA) which is known to stimulate phospholipid- and Ca(2+)-dependent protein kinase (C-kinase) enhanced the proliferation of synovial cells. The proliferation of synovial ...

journal_title：Clinical rheumatology

authors： Yamamoto M,Yasuda M,Shiokawa S,Nobunaga M

更新日期：1992-03-01 00:00:00

abstract：:Seventy-nine patients suffering from rheumatoid factor positive rheumatoid arthritis (RA) were included in this study. In each patient disease activity was assessed three times at two-week intervals during a four-week period. All factors that might possibly influence RA, except atmospheric conditions (AC) were held co...

journal_title：Clinical rheumatology

authors： van de Laar MA,Bernelot Moens HJ,van der Stadt RJ,van der Korst JK

更新日期：1991-12-01 00:00:00

abstract：:Tumour necrosis factor alpha (TNF alpha) and interleukin-2 (IL-2) are potential immunological mediators of pathogenetic changes in rheumatoid arthritis. We measured the concentrations of TNF alpha and IL-2 in plasma from 2 groups of patients suffering from rheumatoid arthritis (RA). One group had high and one had low ...

journal_title：Clinical rheumatology

authors： Espersen GT,Vestergaard M,Ernst E,Grunnet N

更新日期：1991-12-01 00:00:00

abstract：:In an open study, we have assessed the bone/soft tissue uptake index in recent osteoporotic vertebral collapse using scintigraphy. The evolution of these cases was followed-up at 6 months in 22 patients treated with 100 IU of salmon calcitonin plus 500 mg of elemental calcium/10 days per month and in 18 patients treat...

journal_title：Clinical rheumatology

authors： Rico H,Merono E,Del Olmo J,Revilla M

更新日期：1991-09-01 00:00:00

abstract：:A 73-year-old patient, whose hip was completely destroyed by pigmented villonodular synovitis, was successfully treated by a total prosthetic replacement of this articulation. The etiopathogenesis of the illness is uncertain. Its' localization in the hip is, fortunately, a rare occurrence. It can be responsible for fr...

journal_title：Clinical rheumatology

authors： Descamps F,Yasik E,Hardy D,Lafontaine M,Delince P

更新日期：1991-06-01 00:00:00

abstract：:Diffuse systemic sclerosis and the related syndromes were diagnosed in 115 patients during 1977-1987. Sixty-nine patients were available for clinical evaluation and analysis. These included 46 patients with diffuse systemic sclerosis, 2 with limited cutaneous systemic sclerosis, 2 with linear scleroderma, 18 with over...

journal_title：Clinical rheumatology

authors： Panicheewa S,Chitrabamrung S,Verasertniyom O,Vanichaphantu M,Kraisit SO,Chiewsilp P,Vatanasuk M

更新日期：1991-06-01 00:00:00

abstract：:The effects of vitamin C on 1,25(OH)2D3 synthesis in humans were evaluated; the study included 20 females. They were divided into 2 groups. The first of the 10 subjects (age range 55-71) received ascorbic acid at a dose of 150 mg/die i.v. for 10 days; the second 10 subjects (age range 55-69) received a placebo i.v. fo...

journal_title：Clinical rheumatology

authors： Cantatore FP,Loperfido MC,Magli DM,Mancini L,Carrozzo M

更新日期：1991-06-01 00:00:00